BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20260121T235059EST-78461d2Ld8@132.216.98.100 DTSTAMP:20260122T045059Z DESCRIPTION:\nThe Neuro Epilepsy Day 2026: Epilepsy Across Multiple Scales  \n\nThe Neuro Epilepsy Day will be a full-day program\, exploring epilepsy research and treatment across all scales: molecular\, cellular\, circuit\ , and connectome.\n\n\nRegister Now\n\nTo watch online\, click here\n\n\nC all for Abstracts\n\nWe invite undergraduate\, graduate\, and postdoctoral trainees to submit abstracts for poster presentations at The Neuro Epilep sy Day 2026. \n\nWe encourage abstracts at any stage of a project’s develo pment—from literature reviews and research questions to pilot data and ong oing studies.\n\nSubmission deadline: March 23\, 2026\n\nSubmit Your Abstr act Here\n\nSelected abstracts will be featured in the poster session\, an d five outstanding posters will be invited to give a short oral presentati on during the program.\n\n\n\n \n Programme\n Speakers\n The Pierre Gloor Lect ure\n Location\n Sponsors\n Scientific Committee\n \n\n \n Thursday\, May 28\, 2 026\n\n Preliminary Program \n\n \n \n \n 9:15\n \n Arrival & Registration\n \n \n \n 9:30\n \n Lab Tours\n\n Neuroimaging\, EEG/FMRI\, MEG\,\n \n \n \n 10:45\n \n Wel come and Introduction\n\n Boris Bernhardt\, PhD\n Associate Professor of Neu rology and Neurosurgery\n Epilepsy Group Leader (Research)\, The Neuro\n \n \n \n 11:00\n \n Keynote Lectures\n\n Improving Epilepsy Surgery Planning Using MR Fingerprinting\n\n Irene Wang\, PhD\n Research Director and Staff Scient ist\n Cleveland Clinic Epilepsy Center\n\n Networks\n\n Seok-Jun Hong\, PhD\n Associate Professor of Biomedical Engineering Department\, SKKU\n Sungkyunk wan University - 鶹ýվ\n\n Surgical Approaches and Innovations in FCD\n\n Roy William Dudley\, FRCSC\n Assistant Professor\, Department of Pediatric Surgery\, Department of Neurology & Neurosurgery\n Montreal Child ren's Hospital\n\n Alexander G. Weil\, FRCSC\, FACS\n Associate Professor\, Neurosurgeon\, Researcher\, Director\n University of Montreal - Sainte-Just ine Hospital Research Centre\n\n Jeffery Allan Hall\, FRCSC\n Assistant Prof essor of Neurology and Neurosurgery\n Epilepsy Programme\, Neurosurgery Cli nic\, Brain Tumour Clinic\n\n Sami Obaid\, MD\, PhD\, FRCSC Clinical Assist ant Professor\, Neurosurgeon Department of Surgery\, Faculty of Medicine C entre hospitaliser de l'Université de Montréal\n \n \n \n 1:00\n \n Lunch and Po ster Session\n \n \n \n 2:00\n \n Oral Presentations\n \n \n \n 3:00\n \n Coffee Break \n \n \n \n 3:15\n \n Pierre Gloor Lecture\n\n Brain Mosaicism in Epilepsies and Cortical Malformations\n Stéphanie Baulac\, PhD\n Research director and Grou p Leader\n Inserm and Paris Brain Institute (ICM)\n \n \n \n 4:15\n \n Discussion Panel\n\n Samantha Audrain\, PhD \n\n Alexander Barnett\, PhD \n\n Stéphanie  Baulac\, PhD \n\n Andrea Bernasconi\, MD  \n\n Boris Bernhardt\, PhD \n\n Ne da Ladbon-Bernasconi\, PhD  \n\n Sara Lariviere\, PhD  \n\n Raluca Pana\, MD \, FRCP\, CSCN \n\n Myriam Srour\, MDCM\, PhD \n \n \n \n 5:00\n \n Cocktail Rece ption (onsite)\n \n \n \n \n \n\n \n Speakers\n\n Keynotes:\n\n Irene Wang | Improv ing Epilepsy Surgery Planning Using MR Fingerprinting\n\n Dr. Irene Wang is the Research Director and Full Staff at the Cleveland Clinic Epilepsy Cen ter and an Associate Professor of Neurology at the Cleveland Clinic Lerner College of Medicine. Her research advances surgical treatments for MRI-ne gative epilepsy patients through innovative imaging and neurophysiology te chniques. As a trained biomedical engineer with a strong foundation in cli nical neurophysiology and neuroimaging\, Dr. Wang has pioneered the integr ation of advanced imaging into clinical practice to enhance patient care. She has authored over 120 peer-reviewed papers and serves as Associate Edi tor for Epilepsia. Dr. Wang has received continuous support from the Natio nal Institute of Health and serves as a charter member of the NIH Imaging Technology for Neuroscience study section. Dr. Wang also chairs the MRI Da ta Task Force of the ILAE Big Data Commission and serves on the Imaging Ta sk Force of the ILAE Diagnostic Methods Commission.\n \n Improving Epilepsy Surgery Planning Using MR Fingerprinting\n More details to come...\n\n  \n\n Stéphanie Baulac | Pierre Gloor Lecture\n\n Stéphanie Baulac is a Research Director at Inserm and Group Leader at the Paris Brain Institute (ICM) of the MOSAIC Team « Genetic Mosaicism in Epilepsy and Neurodevelopmental Dis orders » Her team implements a comprehensive translational approach spanni ng from the identification and characterization of somatic mutations in br ain tissues obtained from patients undergoing epilepsy surgery to in-depth functional analysis\, combining functional testing on patient-derived bra in organoids\, and mouse models. \n \n Brain Mosaicism in Epilepsies and Cor tical Malformations\n Focal cortical dysplasia type II (FCDII) is a cortica l malformation causing refractory epilepsy\, resulting from developmental somatic mutations in mTOR pathway genes. To understand how these mutations create a mosaic pattern of affected cells and lead to cortical dyslaminat ion\, we performed comprehensive single-nucleus analyses of surgical sampl es from genetically-characterized FCDII patients. By combining genotyping and transcriptomics at single-cell resolution\, we revealed that mutations predominantly affect glutamatergic neurons and astrocytes\, creating dist inct transcriptional programs in both mutated and non-mutated cells. This mosaicism drives cell-type-specific dysregulation of synaptic and neurodev elopmental pathways that likely contribute to epileptogenesis. Notably\, o ur analysis of cytomegalic cells uncovered pronounced alterations in mitoc hondrial metabolism pathways and cellular senescence. We uncover a signatu re associated with cellular senescence in abnormal FCDII cells and further provide evidence in preclinical FCDII mouse models that senolytic agents could offer a novel therapeutic strategy for this disorder.\n\n  \n\n Seok-J un Hong\n\n Seok-Jun Hong\, PhD is an associate professor in the Department of Biomedical Engineering\, and Brain Science and Engineering at Sungkyun kwan University (SKKU) and also affiliated with the Center for Neuroscienc e Imaging Research\, IBS in S. Korea. Before joining to SKKU\, he was a po stdoctoral research fellow in Child Mind Institute at New York\, working w ith Drs. Michael Milham and Adriana Di Martino\, and before that\, in MNI with Dr. Boris Bernhardt. Dr. Hong’s previous research has focused on adva nced in-vivo multimodal magnetic resonance imaging of typical and atypical brain development (epilepsy and autism)\, especially targeting a large-sc ale brain network organization. Building upon expertise in computer scienc e\, statistics and neuroinformatics\, he has developed original approaches to quantitatively describe connectome principles and its developmental pr ocess in the human brain. These days\, his interest is how to inform biolo gical inductive biases learned from the human brain to build up large-scal e biophysical neural network models.\n\n  \n\n Sami Obaïd | Surgical approac hes and innovations in FCD\n\n Dr. Sami Obaïd\, M.D.\, Ph.D.\, is a neurosu rgeon specializing in epilepsy at the Centre hospitalier de l’Université d e Montréal (CHUM) and a Clinical Assistant Professor in the Department of Surgery at the Université de Montréal. He is also a principal investigator at the CHUM Research Centre (CRCHUM)\, where he leads the ONSET lab. His surgical practice is dedicated to epilepsy surgery\, and in 2024\, he was awarded the prestigious FRQS Junior 1 Researcher status. He underwent spec ialized training\, including a fellowship in epilepsy surgery at Yale Univ ersity and a Ph.D. in structural neuroimaging applied to focal epilepsy. D r. Obaïd focuses his clinical and scientific activities on the identificat ion\, selection\, presurgical evaluation\, operative and postoperative man agement of patients with drug-resistant epilepsy through innovative neuroi maging techniques. Recognized early for his contributions to research\, an asteroid was named in his honor: the minor planet Obaïd (21712). He has a lso been named a Distinguished Citizen of Canada for his scientific achiev ements\, listed among the “Top 20 Under 20”\, and one of his articles was awarded Discovery of the Year 2022 at the CRCHUS. He recently had the hono r of serving as a guest co-speaker alongside astronaut Chris Hadfield\, re flecting the reach of his work and his commitment to science communication . A few months ago\, he also signed the Golden Book of the King of Morocco in recognition of his academic and scientific accomplishments. At the ONS ET laboratory\, Dr. Obaïd currently supervises 22 graduate students and tw o research assistants\, actively contributing to the training of the next generation of neuroscientists.\n\n  \n\n \n \n\n \n The Pierre Gloor Lecture\n \n The Pierre Gloor Lecture celebrates the life and legacy of Pierre Gloor (1923–2003)\, who joined The Neuro (Montreal Neurological Institute-Hospit al) in 1952 as a fellow in electroencephalography and neurophysiology. He trained under Wilder Penfield and Herbert Jasper and earned his PhD from M cGill University in 1957. Gloor collaborated closely with clinical and res earch teams at The Neuro in advancing the understanding and treatment of e pilepsy\, gaining international recognition for his contributions to the f ield.\n\n Brain Mosaicism in Epilepsies and Cortical Malformations\n\n Speak er: Stéphanie Baulac\, PhD\n Research director and Group Leader\n Inserm and Paris Brain Institute (ICM)\n\n Focal cortical dysplasia type II (FCDII) i s a cortical malformation causing refractory epilepsy\, resulting from dev elopmental somatic mutations in mTOR pathway genes. To understand how thes e mutations create a mosaic pattern of affected cells and lead to cortical dyslamination\, we performed comprehensive single-nucleus analyses of sur gical samples from genetically-characterized FCDII patients. By combining genotyping and transcriptomics at single-cell resolution\, we revealed tha t mutations predominantly affect glutamatergic neurons and astrocytes\, cr eating distinct transcriptional programs in both mutated and non-mutated c ells. This mosaicism drives cell-type-specific dysregulation of synaptic a nd neurodevelopmental pathways that likely contribute to epileptogenesis. Notably\, our analysis of cytomegalic cells uncovered pronounced alteratio ns in mitochondrial metabolism pathways and cellular senescence. We uncove r a signature associated with cellular senescence in abnormal FCDII cells and further provide evidence in preclinical FCDII mouse models that senoly tic agents could offer a novel therapeutic strategy for this disorder.\n\n  \n\n \n \n\n \n Location\n\n The Montreal Neurological Institute and Hospital is at 3801 University Street\, north of Pine Avenue West\, on the 鶹ýվ U niversity campus opposite the former Royal Victoria Hospital.\n\n Montreal is served by highway Routes 10\, 15\, 20 and 40\, and by Greyhound Bus\, V ia Rail and the P-E-Trudeau airport. In the city\, bus and metro service i s provided by the Société de transport de Montréal (STM).\n\n Wheelchair ac cess\n\n A wheelchair accessible entrance is on University Street north of the main entrance. Another wheelchair accessible entrance is in the loadin g area behind the building: to enter the loading area\, turn into the driv eway south of the main entrance. Please note\, there is no parking in the loading area.\n\n Parking\n\n Parking near the MNI is sometimes difficult. T here are parking meters on University Street and a parking lot north of th e main entrance. To enter the lot\, turn right into the driveway toward Mo lson Stadium.\n\n Information about parking fees\n\n Taxi Stand\n\n There is a taxi stand on University Street across from the main entrance. You may c all a cab from the free taxi phone in the main lobby near the Security Des k.\n\n Access by Public Transportation (STM website)\n\n Bus\n\n There are fo ur bus stops within walking distance:\n\n \n Bus 144 stops at Pine Avenue an d University Street\n Bus 356 stops at Sherbrooke Street and University Str eet (Nightbus)\n Bus 107 stops at Pine Avenue and Docteur Penfield\n Bus 24 stops at Sherbrooke Street and University Street\n \n\n Metro\n\n Take the Me tro Green Line to the 鶹ýվ station. Walk north on University Street and cross Pine Avenue. The main entrance is on the right\, past the flags.\n\n Jeanne Timmins Amphitheatre\n\n \n Enter the main lobby\, turn left\, and go down the hallway to the end.\n Turn right and go down the second hallway u ntil you see another hallway on the left.\n This hallway leads to the Jeann e Timmins Foyer.\n On your right are the Jeanne Timmins Amphitheatre entran ce doors.\n \n \n\n \n Sponsors \n \n\n \n Scientific Committee\n\n Sam Audrain\n \n Alexander Barnett\n\n Boris Bernhardt\n\n Sara Larivière\n\n Raluca Pana\n \n Debbie Rashcovsky\n\n Myriam Srour\n\n  \n\n \n \n\n DTSTART:20260528T131500Z DTEND:20260528T210000Z LOCATION:Jeanne Timmins Amphitheatre\, The Neuro SUMMARY:The Neuro Epilepsy Day 2026: Epilepsy Across Multiple Scales URL:/bic/channels/event/neuro-epilepsy-day-2026-epilep sy-across-multiple-scales-368975 END:VEVENT END:VCALENDAR